Tamoxifen is the main ingredient in the brand mostly sold as Nolvadex. There are numerous other brand names you can find Tamoxifen being sold, but Nolvadex is by far the most popular one as it is the oldest brand. The compound was firstly manufactured by Imperial Chemical Industries (ICI) but then the company was purchased by AstraZeneca.
Nowadays is sold as brand Nolvadex by this pharmaceutical giant company.
Tamoxifen Citrate is the full name of the active substance and this is an orally active medication that is FDA approved and is on the list of essential drugs of the World Health Organization (WHO) which means the product is fairly safe and is very effective.
What is Tamoxifen?
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The compound Tamoxifen (Nolvadex) is an Anti-Estrogen but contrary to popular belief, the compound does not lower estrogen levels but is blocking estrogen activity. That’s because Nolvadex is not an Aromatase Inhibitor (AI) but is actually a Selective Estrogen Receptor Modulator (SERM). This means that it selectively binds to some estrogen receptors.
- In some parts of the body works as an agonist of estrogen activity as soon as binding to those receptors, but in other parts works as an antagonist of estrogen by binding to the receptors.
Tamoxifen – Nolvadex is very similar to Clomiphene – Clomid since this is also a SERM.
Keep in mind that with SERMs, your blood serum levels are not affected, it would locally work boosting or inhibiting estrogen action by taking the place of estrogen from binding to receptors. Only AIs such as Arimidex, Aromasin or Femara are reducing the circulation of estrogen.
Tamoxifen Nolvadex Uses
In medical settings, the compound is mostly used for treating (or can be used for preventing) breast cancer – cancer that requires estrogen. It can be used for females and males for such needs. But males can be prescribed Tamoxifen for gynecomastia whilst women may be prescribed Tamoxifen for infertility issues. There are other medical uses of Nolvadex too.
We highly recommend you to talk to your doctor if you need Nolvadex for a health condition.
However, Tamoxifen Citrate is very popular in bodybuilding settings too. Is used either during the use of aromatized steroids to prevent or treat gynecomastia which can appear as a result of running steroids, or can be used after the course of steroids is stopped as a part of Post Cycle Therapy (PCT) plan.
Nolvadex binds to the estrogen receptors in breast tissues, that’s how it stops gynecomastia and breast cancer. Nonetheless, it is mostly used for PCT plans because Tamoxifen (Nolvadex) can’t help with other estrogen related issues during the use of aromatized steroids. Examples of such issues are bloating, water retention, hypertension, etc.
- For such needs – Aromatase Inhibitors (AIs) are mostly used. Tamoxifen, on the other hand, is one of the best compounds out there for Post Cycle Therapy.
Tamoxifen Citrate – Nolvadex blocks the estrogen from reaching the pituitary gland. This way, your gland releases more gonadotropins which leads to more FSH and LH – the crucial hormone for synthesizing testosterone. Due to the block of estrogen, Nolvadex increases LH and therefore boosts natural testosterone production.
Tamoxifen Nolvadex Side Effects and Dosage
Most people who run Tamoxifen for PCT plans, stack it together with Clomid as they work together for greater results. PCT plans usually last 4 weeks and they are started when all steroids are out of the body.
Nolvadex side effects among men are very rarely reported and usually – only in case too high doses are administered. They usually have increased or decreased libido, insomnia, nausea, fatigue, and a few others.
Dosage of Tamoxifen Citrate depends on whether you need it for PCT or for gynecomastia treatment.
- When used for gynecomastia, dosages range between 20 mg and 80 mg per day, depending on various things.
- In case you run Nolvadex (Tamoxifen) for the PCT plan, then the compound is usually started at 40 mg per day for the first 2 weeks and then is reduced to 20 mg per day for the last 2 weeks.
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Nolvadex – Tamoxifen Citrate is very effective, extremely important, and therefore very popular in the bodybuilding world. Whoever thinks to run steroids should think about a PCT and Tamoxifen is among the best PCT medicines out there.
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